The quick lick above—played by Doug Aldrich of Whitesnake—was inspired by the late Gary Moore.
It begins with a steady, machine-gun barrage of alternate-picked, palm-muted 16th notes and ends with a wild two-step "over-bend" on the low E string, punctuated by a squealing pinch harmonic.
"I play through this lick using strict alternate picking (down-up-down-up) to ensure my rhythms are dead-on accurate. The best way to practice this style of picking is simply to start out slow, paying close attention to your pick stroke's direction.
"When performing the two-step bend on the low G note (low E string, third fret) in bar 4, I'm using both my index and middle fingers to pull the string in toward my palm. The extra finger muscle is all but required to perform this monster bend, as otherwise there's a good chance the string would slip out from under my middle finger."