Limited to just 12,500 examples worldwide, the watch is Seiko's second collaboration with the Queen guitarist. By May's request, it features a gold finish, in reference to the recent "Gold Series" reissues of his solo albums.
The watch's pressed pattern is designed to resemble the texture, finish and coloring of the Red Special, and its nylon strap features vertical stripes designed to resemble guitar strings.
"The two definitely work together – the watch echoes the guitar," May explained in an interview with Seiko, which you can watch below.
The back of the watch sports May's signature, and a unique serial number that will range from 00001/12500 to 12500/12500.
A portion of the proceeds from the sale of the watch will be donated to The Mercury Phoenix Trust, which funds initiatives around the globe relating to HIV/AIDS, and was founded by Queen's surviving members after the band's frontman, Freddie Mercury, died of AIDS-related causes in 1991.
For more information on the watch, which goes on sale on March 1, visit Seiko.