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Tedeschi Trucks Band and Trey Anastasio share smoldering live performance of Derek & the Dominos’ Nobody Knows You When You’re Down and Out

Tedeschi Trucks Band have shared live footage of their performance of Derek & The Dominos’ Nobody Knows You When You’re Down and Out, featuring Phish legend Trey Anastasio.

The live cut is notable for featuring exquisitely phrased solos from Anastasio and Derek Trucks, as well as longtime collaborator Doyle Bramhall II, while Susan Tedeschi handles rhythm and vocals.

Following Why Does Love Got to Be So Sad, it’s our second taste of forthcoming live album Layla Revisited (Live at LOCKN’), which captures a one-off performance of Derek & the Dominos’ iconic Layla and Other Assorted Love Songs in its entirety at the LOCKN' Festival in Arrington, Virginia on August 24, 2019.

Tedeschi and Trucks’ connection to Layla, which features both Eric Clapton and Allman Brothers Band slide guitar great Duane Allman, runs deep: it was released on November 9, 1970, the same day Susan Tedeschi was born; Trucks’ parents were such fans of the record that they named Derek after the band; and Trucks spent 15 years as a member of the Allman Brothers Band and has toured extensively with Clapton.

Layla Revisited (Live At LOCKN’) is out on July 16 via Fantasy Records, and available to preorder (opens in new tab) now.

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Mike is Editor-in-Chief of, in addition to being an offset fiend and recovering pedal addict. He has a master's degree in journalism, and has spent the past decade writing and editing for guitar publications including MusicRadar (opens in new tab), Total Guitar and Guitarist, as well as the best part of 20 years performing in bands of variable genre (and quality). In his free time, you'll find him making progressive instrumental rock under the nom de plume Maebe (opens in new tab).